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The Neurobiology of Diabetes Mellitus and Its Treatment with Natural Medicine


The Neurobiology of Diabetes Mellitus and Its Treatment with Natural Medicine

  
 Clinical observation revealed that almost all diabetes patients develop peripheral neuropathy in the early stage of the disease, 60% of which have parasympathetic neuropathy. So among such basis changes in diabetes mellitus as macro-vascular and micro-vascular changes and neuropathy diabetic neuropathy may play an important role in the development of diabetic complications. Diabetic neuropathy may be one of the initial factors of diabetes mellitus, and is also a complication of diabetes mellitus in the advanced stage of the disease.

The pathological factor of neuropathy has never considered in the treatment of diabetes mellitus. It is believed that no new neurons will generate in the adult person and the damaged neurons will never be regenerated. There is now no chemical or natural medicine for us to treat diabetic neuropathy. Our clinical experimental study starting from l996 based on such a hypothesis that the nerve system may has the ability to repair themselves is to treat the patients of diabetic neuropathy by orally taking the crude extraction from the compound of DanShen (Radix Salviae Miltiorrhizae) et al.

The first effective evidence was observed in l997 that the sole of foot of the patient was sweaty, indicating that this compound may be effective on the diabetic neuropathy.
  In the subsequent studies, most of the neuropathy symptoms of the patients were disappeared or largely improved such as correction of the arrhythmia stopping of titillation and diarrhea, normalization of blood pressure, improvement of impotence and the disappear of the rest pain. The hyperglycemia was also reduced to the normal level when hyperglycemia agent is added and the effects can last more than two years without relapse.
  
   The result suggests that medicine may directly affect the reparation of the damaged neurons and agent treatment of the diabetic neuropathy may be the key part of the diabetic treatment. But the detailed mechanisms are in further investigation. Besides, these neuropathy agents are also effective in the treatment of such diseases the cause of which are still unknown as cardiovascular disease, hypertension, hypotension and hypoglycemia, which may be a more importance result.

By Shu Gang, Yao FengLing

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