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Clinical Study on 500 Cases of Nonspecific Ulcerative Colitis Treated by



Clinical Study on 500 Cases of Nonspecific Ulcerative Colitis Treated by "Qiankun Changkang" Enteroclysm

  
Objective: Clinical Study on the therapeutic effect of retention enema with Qiankun Changkang enteroclysm (decoction for enema in regulating intestine function) on nonspecific ulcerative colitis and its mechanism.

Methods
 (l) The patients were collected according to the criteria set up in 1993 on the Conference of National Non-Inflammatory Intestinal Diseases. Totally 600 cases were treated and observed. They were classified into treated group (500 cases) and control group (100 cases) at random. There is no difference in age, course of disease, seventy of disease substantially;

(2) Treated group: Qiankun-changkang was given by retention enema which consists of Xian Rengu, Rhizoma bletillae, Cortex phellodendron, Radix salviae miltiopphizae, 10g each. Ready for use after preparation. 100ml were given every time, twice per day. 1 course consists of 30 days. After 3 days interval for rest, continue another course;

(3) Control group: 1 amper of xilei powder and l/3 amper of Yunnan Baiyao were added into 200ml distilled water B.i.d., retention enema with 100ml. The course of treatment is similar to that of treated group.

Results: Among 500 cases, 317 cases cured, 103 cases significant effect, and 61 cases effective. The cure rate is 63.4% and total effective rate is 96.3%. Among 100 cases in control group 35 cases cured, 11 cases significant effective, 24 cases effective, 30 cases no effect. The cure rate is 35% and total effective rate 70%. Comparison of the effective the shows that the treated group is much better than the control group. The difference is significant (p<0.0l). In the treated group, there are 140 cases of severe cases. The therapeutic effect of them is especially marked, that is 92 cases cured, 30 cases significant effective, and 12 cases effective. In the 96 mild cases, 60 cases cured 23 cases significant effective, 8 cases effective. The effect is rather poor in 264 cases of moderate degree. 165 cases cures, 50 cases significant effective and effective in 41 cases. Sigmoidoscopy was carried out before and after therapy, the result of this examination shows also the effectiveness of the drug.

Conclusion: Qiankun Changkang enteroclysm is effective in treatment of nonspecific ulcerative colitis.

Shang Rubiao, Li Minghui, Chen Ying, etc
 

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Jing ICP Record No.08105532-2