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Treatment of Senile Diabetic Diarrhea with Traditional Chinese Drugs
wen8 JIm fiff#
Dopatheent of Guntoha,tris>u ProvlncJuI ffesntol ofbohonaI c&mese weclnc.
Th8bedc dl8whea. a nomndctiom
diedch is one of the bondicabo of
diatedcs I1 only comlsts of a smalIer
cotohtheot ds amony ail obe d1$tctJc
comPlicallons such as diatetic calarart or
diabehc coroeq ndoscleret1c crtoPalhy
Accotalng to a pe11amW 1nve5tigation ty
the auther sfor Whc diMa 1s still vere
cmn. rePreamdsg aPPrmmate1y 15 ooq
of all peni1e dmbetic comFliCalloor With
comPllCa1ed canses and chown pathogeorslS
wt are snd no prmeDtive ed thempeude
'o ptocoL, with type n diawt diedea were
rePotad to be wh9factonly thealed wwh Jiang
Tan Thl Xie Feq (ra * if i8 rt
Hrpoglyeermc bo Anh~al Deoochrm)
All the 75 p-ts 1tt dris ares were
dsfinitaly diWsed As havrng sopl1e tyPe Jl
di8beleg Ncatd ty diallhea arcotalng to
the twstic mboa foI dideop
recinndsd by WHO and the patlcots #e
range Ainbog the 40 cases m thC beatInn1
gnup. 27 were un1e and l3 fore Thenop
vW tw 60 to 86 years with an average Of
655 ym The Mn of diatiews mged
wt 5 wt 1o 38 M. W an avempe of
853 years 24 twnts care dewn with
didetes de 60 years of4 wMi 16 got than
disease at young or rmame age and iasted tO
thelT sMy The duthen w1th inforbo
dlarthea was hom l month to 15 yop
avmpng 3 mMs At lhe fust v1sit. oo ca8es
ware foond wh aindea of 5-6 thes a tw.
]4 cun 34 limes a dny nd 6 cases l 2 thes
a day. i2 cares were fomid wjth boc
hePato injury 8 cages with cormny
rtrioscfordric cWp8thy. 7 cases with
cMarl 7 oues wh ren31 lnsufficaenCy nd 9
cares wlth hnyrliPana There wor 6 patiedts
wbo wew comPllcated sedbeously the
two complicallom or N As fOI th6 35 caas
,n the coned grouP 2l ware for and 14
wt Thax agB vtw ftem 6O yon to 87years, averaging 65.7 years. The durallon of
diNs in this group was from 5 years to 37
yMs, with an average of 8.54 years. 23
patients came down with diabetes ther 60
years old, and l2 cases at thch young or
ndddie age and continued to their senillty. The
Won with inndttCnt diarrhea was from
25 days tO l9 months, averaging 3 months. At
their first visit, l5 cases were found With
diWa of 5-6 times a day, 14 cases 3-4 thes
a day and 6 cases l-2 tiIns a day. ll cases
wer found with chronic hepatic injUry, 9
cases with coronary arteriosclerohc
cardioPath, 6 cases with cataract, 5 cases with
renai insufficiency, and 7 cases with
hWa.
TkeraPendc Method8
The patiens in the trethent group wer
treated with Jiang Tang th Xie Fang (W#th
N A Hypoglycetric and ^ntidiarrtwal
DecoctiOn), a selfprepared decochon which
was mad uP of Dang Shen (Radix
CodonoPsis) l5g, Shan Yao opzoma
Dioscoreae) 30g, Chao Bai Zhu toarched
Ma Atractylodis MacrocePhalae) 10g,
Huang Lian opzoma CoPtidis) 5g, Shi LiuYe
(FoliUm Granati) 10g. Bu Gu m thectus
Psoraiae) 10g, Rou Dou KOu (Semn
Mghsticae) l0g, Huang Qi (Radix Astragall)
20g, and He Zi (FructUs Chebulae) 10g. Al
the allove-menoned drugs were put intO
wato and decocted into 300 ml of drug liquid
for ond Mulstalon, 150 ml each hme,
b.i.d. Dan Shen (Radix Salviae MilhOrrhizae)
l0g and Jiang Xiang ougnum Dalbergiae
Odoriferae) 5g were added for those with
coronary heart disease; 60g of Huang Qi-
$adix Astragali) and 30g of Fu Ling (Poria)
with bark were adde fOr those with renal
insufficiency; Chao Shen Qu (Parched Massa
Fermentata Medicinalis) l5g and Ji Ne Jin
(Endothlium Comeum Gigeriae Galll) 10g
fOr those with anoretia; Ge Gen (Radix
Puerariae) 10g and Chao Cang Zhu (parched
ANzoma Atractylodis) l0g for thOse with
hyPerlipenda; and Chao Bai Shao (Parched
Radix Paeoniae Alba) 10g and Shan Zha
(FmtUs CrMgi) 20g for thOse with hepatic
injury. 30 doses made a theraPeutic course. 8
Xiaok Pills (diabehc Pill ]A%A) were added
(L i.d) for those patiens with blood sugar level
higher than l2 mmljL.
2.5 mg of glybenzcyclndde was given
(Li.d) fOr patients in the control grOU tO
contrOl the blood sugar and 2 Pins of Li Zhu
Chang Le (6N$@$, a Preparation of Bacillus
bifidus) for antidiarrhea.
Anajysis fOr ThWeutic Effct
l. Criteria for theraPeutic effeCt:
Clinically cured: Diarrhea is cured with
formed stOOl once a day, and the fasting
blood-sugar varies frOm 5.9 tO 6.6 mmljL.
ttis sitllation should last at least 6 months.
ReInarkably twroved: DiaIrha is cured, with
defecation once a day. The fasting bloodsugar
is $7.2 mmol/L, with stable condihon at least
6 months. Failed: There is no obvious
wtvement of the symPtoths, or diarrhea
recurs within a short period of tim. The
fashng blood-sugar level is not Inarkedly
reduced or keP at 38.5 nunolIL.
2. Therapehc results: hi the trCatInCnt
grouP, 28 cases were clinically cured (70.0%),
ll remarkaly twroved (27.5%) and l failed
(2.5%). The total effective rate was 97.5%. In
the contrOl grouP, 23 cases were clinically
cured (65.7%), l0 reInarably twroved
(28.6%) and 2 patients (5.7%) ineffechve. The
total effective rate was 94.3%. The theraPeuhc
Wts wer basically siInilar (P>0.05) for
both grous.
Case ExamPle
Liu, male, 85 years old, paid his first
visit on Januny 3, l992. He had suffered frOIn
diNs for W than 30 years With a history
of iniwttten diarrhea for 5 years. The
diWa had aggravated in recent one month,
7~8 times a day. The stOol was sInall in
quantity and thin in featUr, containing
undigested food. There was no red or white
rOPy pus and no bacterium in bacteriUIn
culta of stool. Dwing exndnation, he was
found with a thin body, a gloomy face, a dark
and purple tongue with then, White and greasy
coating, and thin, deep and weak pulse.
Typical symPtOms, such as overeating,
oveforng, diuresis and lose of body weight,
wer not obvious. The fasting blood sugar was
l2'4 mrnlfL. ECG showed left anterior
fascicular block. Other extalnation inde
showed: urea nitrogen l0.2 nunolfL, creabon
l50 mmlfL and carbon dioxide cOmbndn8
power 29 mmolIL. Differentiation b)
traditional Chinese medicine: deficiency o]
both the spleen and kldney, sichng of clear qi,
deficiency of qi with blood stasis. Prescription:
Dang Shen (Radix Codonopsis) 15g, Shan YaO
(anzoma Dioscoreae) 30g, Chao Bai Zhu
(Parched arizoma Atractylodis Macro-
cePhalae) l0g, Huang Lian (ANzoma CoPhdis:
5g, Bu Gu AN (FructUs Psoraleae) l0g, Rou
Dou Kou (Semen Myristicae) l0g, Huang Qi
(Radix Astragali) 20g, He Zi thectUs
Chebulae) 10g, Dan Shen (RAnx Salviae
Miltiorrhizae) 10g and Jiang Xiang (Ligntnn
Dalbergiae Odorifera) 5g. The diarrhea
disaPPeared and blood sugar was lowered tO
5.9~6.2 InInMi after a one-month trCanent.
Ins stool was normal and blood sugar was
stable during a follow-up fOr six months.
Conunent
~It is found by the author in his long
clinical practice that senile tyPe II diabetes
comPlicated with inttwttent diMa is also
very cornmon ljke type I diabetes cOmPllcated
With diarrhe. Deficiency of the sPleen-qi and
deficiency of qi in Iniddiejiao go through the
whoe course of diabetes. Senile diabetes has a
long course of disease and can not be cured
easily. Dysfimction of the spleen in transport
and untfansformallon of the Iddney-qi induced
by diabetes often lead to diabetic diarrhea.
Jiang Tang ztu Xie Fang (ra W kpe H
HyPoglycendc and Antidiarrheal Decochon)
may strengthen the sPleen, rePenish the
kidney, stOP the diarrhea, and regulate the
fimction of the intestines. It also has a funchon
to reduce the blood-sugar. In the decoction,
Dang Shen (Radix Codonopsis) can rePlenish
qi in the taldiejiao, regUlate funchons of the
stomach and intestines, and relieve thest and
resilessness. As a good hypoglycendc dmg,
Huang Qi peadix Astragall) can be used as a
Inain trig together with Shan Yao (anzoma
Dioscoreae), Ge Gen- (Radix PUerallae) and
In Mu (Rhizma Anemarrhenae) to treat
diabetes. This has been recorded in Yi Xue
Thong Zhong Can Xi Lu (E#$op#M&,
Records of Monal Chinese Medicine in
CombinW with Westem Medicine). Shan
Yao (ANzoma Dioscoreae) is mainly used to
treat the diseases of bee organs, the lungs,
the spleen and stomach. It has the achons of
Mshing the kidney-qi, strengthening the
sPleen and stomah, and stoPPing diarrhea
according to Ben Cao Gang Mu ($$mR
Compendum Of Materta Medica). Dr. Shi
JinIn, a haous coniemoraIy doctor of
tradihonal Chinese medicine, was very
k
Astragali) in combination with Shan Yao
(ANzoma Dioscoreae) as a pajx of effeChve
drugs to treat diabetes. Bai Zhu (Rhizoma
the sPleen, promote its transformallye funchon,
and edrinate damPness to stoP diarrhea. It is
confirmed by modem medicine that Bai Zhu
(ANzoma Atractylodis MacrocePhalae) has
also an action of lowering blood sugar.
Combination of Bu Gu ze ooctUs Psoraleae)
and Rou Dou KOu (Semen Myrishcae) may
..
invigoat the spleen and kidney, and relieve
diaIrhea. He Zi (Frutus Chebulae) (sour
navor) and shi Liu Ye (Folinm Granati) have
good actions of astringency, antidiarrhea and
lowering blood sugar. Huang Lian (ANzoma
Coptidis) can clear the heat and Purge the fire.
There are some rePOrts POinting Oll that
Mnistration of Huang Lian (anzoma
Coptidis) 3g daily may cure diabetes. To sum
up, the nine ingredients in dris decoction are
mutllally benefited and strCngthened, with no
adverse side-effects found during a long-
Period Mnistration.
(Translated by Zhu Hanting $ffi4)
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